Search results for " triazolium salts"

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Development and characterization of co-loaded curcumin/triazole-halloysite systems and evaluation of their potential anticancer activity.

2014

Abstract Positively charged halloysite nanotubes functionalized with triazolium salts (f-HNT) were employed as a carrier for curcumin molecules delivery. The synthesis of these f-HNT new materials is described. Their interaction with curcumin was evaluated by means dynamic light scattering (DLS) and UV–vis spectroscopy in comparison with pristine unmodified HNT (p-HNT). The curcumin load into HNT was estimated by thermogravimetric analysis (TGA) measurements, while the morphology was investigated by scanning electron microscopy (SEM) techniques. Release of curcumin from f-HNT, at three different pH values, by means of UV–vis spectroscopy was also studied. Furthermore, different cancer cell …

Thermogravimetric analysisCurcuminCell SurvivalScanning electron microscopeTriazolePharmaceutical ScienceAntineoplastic Agentsengineering.materialHalloysiteSettore MED/13 - EndocrinologiaDrug Incompatibilitychemistry.chemical_compoundhalloysite nanotubes triazolium salts drug carrier curcumin in vitro anticancer activityDynamic light scatteringCell Line TumorHumansTechnology PharmaceuticalOrganic chemistrySolubilityCell ProliferationSettore CHIM/02 - Chimica FisicaDrug CarriersNanotubesSettore CHIM/06 - Chimica OrganicaTriazolesDrug LiberationchemistryThermogravimetryMicroscopy Electron ScanningengineeringCurcuminClayAluminum SilicatesDrug carrierNuclear chemistry
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